Irish Air Corps Toxic Chemical List Update – Dichloromethane (DCM)

We have just added a link to information on Dichloromethane from PubChem the Open Chemistry Database. Please have a look at green links on our chemical info page here. We will add more on a regular basis.

It is interesting to note the number of illnesses associated with or suspected from Dichloromethane exposure. How many colleagues do we know who have died or are affected by some of the following?

  • Biliary Cancer
  • Blood Cancers
  • Brain Cancer
  • Breast Cancer
  • Cervical Cancer
  • Carbon Monoxide Poisoning*
  • Dizziness
  • Drowsiness
  • Irritation of eyes, skin;
  • Lassitude (weakness, exhaustion)
  • Liver Cancer
  • Lung Cancer
  • Mammary Gland Tumours
  • Miscarriage
  • Nausea
  • Optic Neuropathy
  • Prostate Cancer
  • Phosgene poisoning

Dichloromethane is reasonably anticipated to be a human carcinogen (B2) based on sufficient evidence of carcinogenicity from studies in experimental animals.

Dichloromethane also goes by the synonyms below .

  • Bichloride, Methylene
  • Chloride, Methylene
  • Dichloride, Methylene
  • Methylene Bichloride
  • Methylene Chloride
  • Methylene Dichloride
  • Solaesthin

*Human exposure is mainly due to inhalation and its bio-transformation by the hepatic mixed function oxidases leads to formation of carbon monoxide (CO). Simultaneous exposure to Dichloromethane and increased ambient CO results in undesirably increased carboxyhemoglobin (COHb) formation, which predisposes to carboxyhemoglobinemia with the central nervous system as the primary target organ of toxicity.

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